Under limited supervision of the PI, Section Administrator and Laboratory Manager, provides technical support to the Pancreatic Islet and Regulatory T Cell Transplantation Research Lab at the Department of Surgery by performing moderately complex laboratory techniques and teaching basic laboratory techniques. May oversee daily operations of the laboratory. Completes and maintains accurate records of performed duties. Follows and may assist in developing and improvements of laboratory standard operating procedures. Assists in development of laboratory procedures to ensure accurate collection and analysis of laboratory samples or research data. Utilizes research methods requiring a high degree of proficiency to achieve established research objectives. Evaluates existing methods and objectives.
70% Facilitate/contribute to the clinical activities of the laboratory:
Is responsible for Current Good Manufacturing Practicies (cGMP) facility and reagent preparation for the human pancreatic islet isolation
Assists during human islet isolation process
Prepares supplies in the cGMP facility and routinely checks supplies inventory
Performs quality control and release criteria tests of final islet product in compliance with internal Standard Operating Procedures (SOPs), lab policies and applicable regulations
Assists in equipment maintenance and troubleshooting
Assists in materials preparation, washing and sterilization
Assists in drafting and improvements of SOPs and other laboratory documentation
30% Facilitate/contribute to research activities of the laboratory:
Contributes to the research projects/programs being conducted in the laboratory with specific skills from an extensive, demonstrated background and technical expertise in biological science and biochemistry.
Is responsible for laboratory housekeeping, including equipment maintenance and laboratory inventory.
Helps in data analysis, description of laboratory materials and methods to manuscripts and grant proposal, assists in manuscripts and grant proposals submission processes.
Performs routine library work, including finding literature and copying articles.
Organizes data into professional format, summarizes results, and presents data to PI and in lab meetings.
Effectively communicates, coordinates, and troubleshoots team-based research efforts through participation in laboratory and research meetings.
Maintains clear, accurate, complete, and timely reports of experiments.
Maintain records to ensure compliance with biosafety, radiation safety, animal protocols, compliance reports, instrument maintenance, and supply orders.
Notify PI of any potential violations of regulations.
Supervises and trains trainees and other lab personnel in research techniques, instruments, laboratory methods, procedures, and safety.
Helps monitor compliance with institutional, state, and federal regulatory policies, procedures, directives, and mandates.
Specifically maintains records for compliance (purchasing, compliance with institutional protocols, etc).
Participates in research with laboratory animals.
Other duties as assigned.
Knowledge in relevant the biological sciences or chemistry required
Basic skills in mammalian cell culture procedures required
Basic knowledge of aseptic techniques required
Knowledge of regulatory policies and procedures required
Problem-solving skills required
Attention to detail required
Organizational skills required
Ability to learn new research techniques or methods required
Ability to work independently and as part of a team required
Knowledge of Microsoft Office package required
Analytical skills required
Verbal and written communication skills required
Ability to train others required
Deep knowledge of aseptic techniques preferred
Knowledge of cGMP/cGLP regulations related to the laboratory work preferred
Knowledge of sterilization techniques preferred
Experience in laboratory inventory systems preferred
Experience in working in the clean room environment preferred
Familiarity with grant preparation preferred
Knowledge of statistical analysis and statistical software preferred
Education, Experience or Certifications:
Bachelorâ™s Degree in the field of biological sciences required
Advanced degree in the field of biological sciences preferred
A minimum of 3 years of laboratory experience in the field of cell biology, cell therapy or other related field required
Experience in laboratory work accordingly to current Good Manufacturing Practices and laboratory Practices (cGMP/cGLP) regulations preferred
Experience in laboratory rodents handling and aseptic techniques in rodent survival surgery preferred
Contact information for at least 3 supervisory references
Note: When applying, all required documents MUST be uploaded under the Resume/CV section of the application.
The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via the Applicant Inquiry Form.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
Internal Number: JR02627
About University of Chicago
One of the world's premier academic and research institutions, the University of Chicago has driven new ways of thinking since our 1890 founding. Today, UChicago is an intellectual destination that draws inspired scholars to our Hyde Park and international campuses, keeping UChicago at the nexus of ideas that challenge and change the world.