The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the ‘go-to’ organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.
Vector technology lies at the heart of GTP due to the contributions of the Wilson Lab. GTP has a long track record of success in developing novel vector technologies, manufacturing platforms and analytics as well as distributing vectors for research purposes. Once successful in the research environment, the vectors must be transferred to the clinic which requires expertise both regarding vector manufacturing and characterization. Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide, produces vectors in support of IND-enabling research, develops and conducts GLP assays, oversee sCMO’s in vector production and is expanding to perform state-of-the-art process development.
Due to significant growth, the Vector Core is looking for a new Senior Director of Analytics to lead cross-functional teams responsible for assay development, quality control testing and vector release in support of research, IND-enabling studies, and clinical trials.
As the Senior Director, you will lead and drive strategy as it pertains to vector characterization and quality control. You will oversee the activities of and develop/mentor a high-performing team in multiple functional areas which are inclusive of Assay Development, Research Quality Control, GLP Quality Control and Physical/Chemcial Quality Control. You will implement metrics to track and manage completion of objectives and projects. Interface with external sponsors and internal teams to build strategies to support global initiatives, prepare presentations and other materials for external meetings, regulatory filings, publications, and grant applications. Working closely with the Executive Director of Vector Operations (EDVO) and Project Management, you will develop testing plans, budgets, and timelines, providing timely and accurate information to Management and Project Teams regarding the delivery of fully characterized vector for IND-enabling studies and clinical trials. You will develop analytical testing plans for clinical programs at CMOs and direct the transfer GLP assay technologies to CMO’s and CRO’s as well as pharmaceutical partners.
You will also work closely with the EDVO and contract partners in the development of GxP vector testing facilities, overseeing construction and validations. Partnering with Talent Acquisition and Senior Leadership, you will develop recruitment strategies to support growth and expansions to provide optimal Analytics development and testing services.
Internal Number: 38615
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.