The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the ‘go-to’ organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.
We are currently looking Research Specialist D, to support research efforts in the areas of airway/pulmonary gene therapy and AAV vaccines for airborne infectious disease.
As a Research Specialist D, you will create recombinant adeno-associated viral vectors expressing various gene products, including antibodies against infectious viruses. You will examine the onset and stability of vector-mediated expression in cells in culture. You will participate in the design of animal studies and will conduct the experiments in various animals that include, but not limited to, mice and NHP to characterize the expression and safety profile of multiple recombinant adeno-associated viral vectors. You will develop and conduct in vitro assays to determine the viral load in various tissues (e.g. lung, brain, liver) of animal models following viral challenge. You will perform multiplex data analysis using computer programs and prepare scientific presentations as well as participate in manuscript preparation. You will be able to work independently, develop collaborations with co-workers and peers at other labs and troubleshoot as needed.
Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures.
Internal Number: 36923
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.